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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFF
All Species:
18.18
Human Site:
S223
Identified Species:
40
UniProt:
Q9GZY8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZY8
NP_064579.3
342
38465
S223
E
D
G
A
N
L
S
S
A
R
G
I
L
S
L
Chimpanzee
Pan troglodytes
XP_516131
372
41638
S253
E
D
G
A
N
L
S
S
A
R
G
I
L
S
L
Rhesus Macaque
Macaca mulatta
XP_001110642
341
38439
S222
E
D
G
A
N
L
S
S
A
R
G
I
L
S
L
Dog
Lupus familis
XP_850079
342
38482
S223
E
D
G
A
N
L
S
S
A
R
G
I
L
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCP5
291
32913
L192
R
R
A
Y
Q
Q
I
L
D
V
L
D
E
N
R
Rat
Rattus norvegicus
Q4KM98
218
24952
R119
T
P
Q
S
E
E
I
R
A
V
G
R
L
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519323
251
27935
K152
I
R
A
V
G
R
L
K
R
E
R
S
M
S
E
Chicken
Gallus gallus
XP_001233530
330
37495
S210
E
D
G
T
N
L
Y
S
A
R
G
I
L
S
F
Frog
Xenopus laevis
Q6DD53
219
24655
R120
T
P
Q
S
E
E
I
R
S
S
G
H
L
K
R
Zebra Danio
Brachydanio rerio
Q503U3
275
31342
S176
S
Q
N
L
N
S
A
S
G
V
L
N
Y
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198768
213
23716
I113
R
T
M
T
L
D
E
I
S
F
P
T
V
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
97.6
95
N.A.
80.1
60.5
N.A.
63.1
81.5
42.4
45.3
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
90.3
98.2
97
N.A.
82.4
62.8
N.A.
67.5
88.8
50.2
61.4
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
100
100
100
N.A.
0
20
N.A.
6.6
80
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
6.6
26.6
N.A.
13.3
80
26.6
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
37
0
0
10
0
55
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
0
10
0
0
10
0
0
10
0
0
10
% D
% Glu:
46
0
0
0
19
19
10
0
0
10
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% F
% Gly:
0
0
46
0
10
0
0
0
10
0
64
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
28
10
0
0
0
46
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
19
10
% K
% Leu:
0
0
0
10
10
46
10
10
0
0
19
0
64
0
37
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
10
0
55
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
19
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
19
0
10
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
19
0
0
0
10
0
19
10
46
10
10
0
0
28
% R
% Ser:
10
0
0
19
0
10
37
55
19
10
0
10
0
55
0
% S
% Thr:
19
10
0
19
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
28
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _